After graduated from Institut Teknologi Sepuluh Nopember Surabaya (ITS), Ni Nyoman Trisnasari starting her career at Hughes Communications Inc, Los Angeles, USA as Junior System Engineer. She then worked as Program Manager at Lockheed Martin Corporation, Pennsylvania, USA and became Vice President of Communications Network at Asia Cellular Satellite (ACeS), a consortium organization in South East Asia. After served as VP at ACeS, she worked as Development Director at PT Inmarsat Indonesia, a subsidiary of Inmarsat Plc, UK. During this period, she continued her study in some areas: International Business at UCLA, Los Angeles; Telecommunicaton Engineering at Temple University, Pennsylvania and Master of Management at Executive Program - Bina Nusantara University. After finished her study, she became Development Director for S2 M FZCO, Dubai (cooperate with Motorola), then joined Aspiro TV, Oslo, Norway as Senior Programme Manager. She finally joined ASYST as Chief Technical Officer (CTO) in 2011.